Litopenaeus vannamei is the most commonly cultured shrimp in Latin America and Southeast Asia, representing over 90 % of total shrimp production. India with its 8,118 km of coastline and 1.24 million Ha of brackish water area is the second shrimp producer in the world, with Andhra Pradesh being India’s largest vannamei farming area. Andra Pradesh, situated on the southern coast of the country, has 974 km of coastline and 175,000 Ha of brackish water. Andhra Pradesh has gradually increased its share in total marine exports of the country, with the United States and Vietnam as the main export markets. Currently, the state’s L. vannamei aquaculture is facing different issues and challenges to achieve sustainability related to diseases outbreaks, lack of availability of quality seed, high feed costs, unauthorized farming, international price fluctuations, less demand in the domestic market, and others. If farmers implement Better Management Practices (BMP) and biosecurity in L. v